Contribution of a New Mutation in parE to Quinolone Resistance in Extended-Spectrum-β-Lactamase-Producing Escherichia coli Isolates
- 1 August 2007
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 45 (8), 2740-2742
- https://doi.org/10.1128/jcm.01093-07
Abstract
Mutations in the quinolone resistance-determining regions of gyrA , gyrB , parC , and parE were studied in 30 fluoroquinolone-resistant clinical isolates of Escherichia coli producing extended-spectrum β-lactamases. Ten isolates showed a mutation in parE that was significantly associated with an increase in the MIC for fluoroquinolones.Keywords
This publication has 15 references indexed in Scilit:
- High presence of extended-spectrum β-lactamases and resistance to quinolones in clinical isolates of Escherichia coliMicrobiological Research, 2007
- In Vivo Selection of Fluoroquinolone-Resistant Escherichia coli Isolates Expressing Plasmid-Mediated Quinolone Resistance and Expanded-Spectrum β-LactamaseAntimicrobial Agents and Chemotherapy, 2006
- Mechanisms of quinolone resistance in Escherichia coli and Salmonella: Recent developmentsInternational Journal of Antimicrobial Agents, 2005
- High incidence of extended-spectrum β-lactamases among outpatient clinical isolates of Escherichia coli: a phenotypic assessment of NCCLS guidelines and a commercial methodDiagnostic Microbiology and Infectious Disease, 2004
- Uso de quinolonas y resistenciaEnfermedades Infecciosas y Microbiología Clínica, 2004
- Mutation Rate and Evolution of Fluoroquinolone Resistance in Escherichia coli Isolates from Patients with Urinary Tract InfectionsAntimicrobial Agents and Chemotherapy, 2003
- Escherichia coli y Klebsiella pneumoniae productores de betalactamasas de espectro extendido en hospitales españoles (Proyecto GEIH-BLEE 2000)Enfermedades Infecciosas y Microbiología Clínica, 2003
- Epidemiological Investigation of Fluoroquinolone Resistance in Infections Due to Extended‐Spectrum β‐Lactamase–ProducingEscherichia coliandKlebsiella pneumoniaeClinical Infectious Diseases, 2001
- Evolución de la resistencia microbiana a fluorquinolonas en un hospital terciarioActas Urológicas Españolas (English Edition), 2000
- Association between double mutation in gyrA gene of ciprofloxacin-resistant clinical isolates of Escherichia coli and MICsAntimicrobial Agents and Chemotherapy, 1994