Beneficial impact of high-field intraoperative magnetic resonance imaging on the efficacy of pediatric low-grade glioma surgery
- 1 March 2016
- journal article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Neurosurgical Focus
- Vol. 40 (3), E13
- https://doi.org/10.3171/2015.11.focus15530
Abstract
OBJECTIVE Intraoperative MRI (iMRI) is assumed to safely improve the extent of resection (EOR) in patients with gliomas. This study focuses on advantages of this imaging technology in elective low-grade glioma (LGG) surgery in pediatric patients. METHODS The surgical results of conventional and 1.5-T iMRI-guided elective LGG surgery in pediatric patients were retrospectively compared. Tumor volumes, general clinical data, EOR according to reference radiology assessment, and progression-free survival (PFS) were analyzed. RESULTS Sixty-five patients were included in the study, of whom 34 had undergone conventional surgery before the iMRI unit opened (pre-iMRI period) and 31 had undergone surgery with iMRI guidance (iMRI period). Perioperative data were comparable between the 2 cohorts, apart from larger preoperative tumor volumes in the pre-iMRI period, a difference without statistical significance, and (as expected) significantly longer surgeries in the iMRI group. According to 3-month postoperative MRI st...Keywords
This publication has 16 references indexed in Scilit:
- Intraoperative magnetic resonance imaging to reduce the rate of early reoperation for lesion resection in pediatric neurosurgeryJournal of Neurosurgery: Pediatrics, 2012
- Importance of intraoperative magnetic resonance imaging for pediatric brain tumor surgerySurgical Neurology International, 2012
- Intraoperative MRI-guided resection of glioblastoma multiforme: a systematic reviewThe Lancet Oncology, 2011
- Multidisciplinary management of childhood brain tumors: a review of outcomes, recent advances, and challengesJournal of Neurosurgery: Pediatrics, 2011
- Dual-room 1.5-T intraoperative magnetic resonance imaging suite with a movable magnet: implementation and preliminary experienceNeurosurgical Review, 2011
- Application of intraoperative high-field magnetic resonance imaging in pediatric neurosurgeryJournal of Neurosurgery: Pediatrics, 2009
- Initial Management of Childhood Brain Tumors: Neurosurgical ConsiderationsJournal of Child Neurology, 2008
- Intraoperative MRI for interventional neurosurgical procedures and tumor resection control in childrenChild's Nervous System, 2006
- Intraoperative Portable 0.12-Tesla MRI in Pediatric NeurosurgeryPediatric Neurosurgery, 2006
- Use of a compact intraoperative low-field magnetic imager in pediatric neurosurgeryChild's Nervous System, 2004