Biochemical modification of the toxicity and the anti-tumour effect of 5-fluorouracil and cis-platinum by WR-2721 in mice
- 31 December 1992
- journal article
- Published by Elsevier BV in European Journal Of Cancer
- Vol. 28 (12), 2017-2024
- https://doi.org/10.1016/0959-8049(92)90251-v
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- The cellular interaction of 5-fluorouracil and cisplatin in a human colon carcinoma cell lineEuropean Journal Of Cancer, 1996
- Effects of the modulating agent WR2721 and its main metabolites on the formation and stability of cisplatin-DNA adducts in vitro in comparison to the effects of thiosulphate and diethyldithiocarbamateBiochemical Pharmacology, 1992
- Thymidylate synthase from untreated human colorectal cancer and colonic mucosa: Enzyme activity and inhibition by 5-fluoro-2′-deoxyuridine-5′-monophosphateEuropean Journal of Cancer and Clinical Oncology, 1991
- Effects of the combination of acivicin and cis-diammine-dichloroplatinum(II) on thymidylate synthesis of A549 lung cancer cellsBiochemical and Biophysical Research Communications, 1989
- The Role of Drug Sequence in Therapeutic Selectivity of the Combination of 5-Fluorouracil and Cis-PlatinSelective Cancer Therapeutics, 1989
- Comparative behavioral toxicity of four sulfhydryl radioprotective compounds in mice: WR-2721, cysteamine, diethyldithiocarbamate, and N-acetylcysteinePharmacology & Therapeutics, 1988
- Clinical trials of WR-2721 prior to alkylating agent chemotherapy and radiotherapyPharmacology & Therapeutics, 1988
- The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenograftsEuropean Journal of Cancer and Clinical Oncology, 1982
- Interactions of platinum complexes with the essential and nonessential sulfhydryl groups of thymidylate synthetaseBiochemistry, 1977
- S-[2-(.omega.-Aminoalkylamino)ethyl] dihydrogen phosphorothioates and related compounds as potential antiradiation agentsJournal of Medicinal Chemistry, 1969