Role for Matrix Metalloproteinase-2 in Oxidized Low-Density Lipoprotein–Induced Activation of the Sphingomyelin/Ceramide Pathway and Smooth Muscle Cell Proliferation
- 3 August 2004
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 110 (5), 571-578
- https://doi.org/10.1161/01.cir.0000136995.83451.1d
Abstract
Background— Oxidized LDLs (oxLDLs) and matrix metalloproteinases (MMPs) are present in atherosclerotic lesions. OxLDLs activate various signaling pathways potentially involved in atherogenesis. OxL...This publication has 32 references indexed in Scilit:
- Deficiency of Gelatinase A Suppresses Smooth Muscle Cell Invasion and Development of Experimental Intimal HyperplasiaCirculation, 2003
- Oxidized LDL-Induced Smooth Muscle Cell Proliferation Involves the EGF Receptor/PI-3 Kinase/Akt and the Sphingolipid Signaling PathwaysArteriosclerosis, Thrombosis, and Vascular Biology, 2002
- Does the coronary risk factor low density lipoprotein alter growth and signaling in vascular smooth muscle cells?The FASEB Journal, 2002
- Extracellular proteolysis in the development and progression of atherosclerosisBiochemical Society Transactions, 2002
- The new synthetic matrix metalloproteinase inhibitor (Roche 28-2653) reduces tumor growth and prolongs survival in a prostate cancer standard rat modelOncogene, 2002
- The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasisTrends in Cell Biology, 2001
- The Oxidative Modification Hypothesis of Atherosclerosis Does It Hold for Humans?Trends in Cardiovascular Medicine, 2001
- Unaltered Secretion of β-Amyloid Precursor Protein in Gelatinase A (Matrix Metalloproteinase 2)-deficient MiceOnline Journal of Public Health Informatics, 1997
- A Possible Role for MMP-2 and MMP-9 in the Migration of Primate Arterial Smooth Muscle Cells through Native MatrixAnnals of the New York Academy of Sciences, 1994
- The pathogenesis of atherosclerosis: a perspective for the 1990sNature, 1993