Collagen Membranes: A Review
Top Cited Papers
- 1 February 2001
- journal article
- research article
- Published by Wiley in The Journal of Periodontology
- Vol. 72 (2), 215-229
- https://doi.org/10.1902/jop.2001.72.2.215
Abstract
Collagen materials have been utilized in medicine and dentistry because of their proven biocompatability and capability of promoting wound healing. For guided tissue regeneration (GTR) procedures, collagen membranes have been shown to be comparable to non-absorbable membranes with regard to probing depth reduction, clinical attachment gain, and percent of bone fill. Although these membranes are absorbable, collagen membranes have been demonstrated to prevent epithelial down-growth along the root surfaces during the early phase of wound healing. The use of grafting material in combination with collagen membranes seems to improve clinical outcomes for furcation, but not intrabony, defects when compared to the use of membranes alone. Recently, collagen materials have also been applied in guided bone regeneration (GBR) and root coverage procedures with comparable success rates to non-absorbable expanded polytetrafluoroethylene (ePTFE) membranes and conventional subepithelial connective tissue grafts, respectively. Long-term clinical trials are still needed to further evaluate the benefits of collagen membranes in periodontal and peri-implant defects. This article will review the rationale for each indication and its related literature, both in vitro and in vivo studies. The properties that make collagen membranes attractive for use in regenerative therapy will be addressed. In addition, varieties of cross-linking techniques utilized to retard the degradation rate of collagen membranes will be discussed.Keywords
This publication has 68 references indexed in Scilit:
- Clinical trial of cross‐linked human type I collagen as a barrier material in surgical periodontal treatmentJournal of Clinical Periodontology, 1995
- Heparan Sulfate and Fibronectin Improve the Capacity of Collagen Barriers to Prevent Apical Migration of the Junctional EpitheliumThe Journal of Periodontology, 1991
- Clinical Evaluation of a Biodegradable Collagen Membrane in Guided Tissue RegenerationThe Journal of Periodontology, 1990
- Scanning Electron Microscopic Observations of Cell Population and Bacterial Contamination of Membranes Used for Guided Periodontal Tissue Regeneration in HumansThe Journal of Periodontology, 1990
- An Evaluation of New Attachment Formation Using a Microfibhllar Collagen BarrierThe Journal of Periodontology, 1988
- Partial Regeneration of Periodontal Tissues Using Collagen BarriersThe Journal of Periodontology, 1988
- A Longitudinal Study Comparing Scaling, Osseous Surgery and Modified Widman ProceduresThe Journal of Periodontology, 1988
- Prevalence, Location, and Patency of Accessory Canals in the Furcation Region of Permanent MolarsThe Journal of Periodontology, 1978
- Results Following Three Modalities of Periodontal TherapyThe Journal of Periodontology, 1975
- Histogenesis of Repair Following Osseous SurgeryThe Journal of Periodontology, 1970