Parthenogenic Origin of Benign Ovarian Teratomas
- 9 January 1975
- journal article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 292 (2), 63-66
- https://doi.org/10.1056/nejm197501092920202
Abstract
To determine the origin of benign cystic teratomas of the ovary, chromosome-banding studies were done on normal tissues and teratomas from five patients. The normal tissues were heterozygous (+/-) for 17 chromosome polymorphisms at or near the centromere, whereas the teratomas were uniformly homozygous (+/+ or -/-). These findings and those employing electrophoretic variants indicate that ovarian teratomas are parthenogenic tumors that arise from a single germ cell after the first meiotic division.Keywords
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