Syringometaplasia: variants and underlying mechanisms
- 13 October 2015
- journal article
- review article
- Published by Wiley in International Journal of Dermatology
- Vol. 55 (2), 142-148
- https://doi.org/10.1111/ijd.13040
Abstract
Syringometaplasia is an adaptive, benign, metaplastic cellular process that affects the eccrine ducts and glands in response to a variety of physiological or pathological stimuli. Different subtypes of syringometaplasia have been described, including the squamous, mucinous, and adenomatous types. These metaplastic changes have been reported in association with chemotherapeutic agents, as well as with a variety of skin disorders including multiple infectious, neoplastic, and inflammatory skin diseases. In this review, we attempt to shed light on the different patterns of syringometaplasia, its pathogenesis, the plethora of skin conditions in which it may be observed, and the differential diagnoses that should be considered.This publication has 46 references indexed in Scilit:
- Eccrine squamous syringometaplasia associated with vemurafenib therapyJournal of the American Academy of Dermatology, 2012
- A Case of Reactive Eccrine SyringofibroadenomaAnnals of Dermatology, 2011
- Syringotropic Mycosis FungoidesThe American Journal of Surgical Pathology, 2011
- Eccrine Squamous Metaplasia and Periadnexal Granulomas: New Cutaneous Histopathologic Findings in Cardiofaciocutaneous SyndromePediatric Dermatology, 2009
- Eccrine squamous syringometaplasia associated with sunitinib therapyJournal of the European Academy of Dermatology and Venereology, 2007
- Cutaneous oncocytoma – a report of three cases and review of the literatureJournal of Cutaneous Pathology, 2006
- Imatinib-induced eccrine squamous syringometaplasiaJournal of the American Academy of Dermatology, 2006
- Eccrine squamous syringometaplasia in a patient with systemic lupus erythematosusJournal of the European Academy of Dermatology and Venereology, 2006
- Eccrine squamous syringometaplasia in intertriginous areasBritish Journal of Dermatology, 1996
- Mucinous syringometaplasiaJournal of the American Academy of Dermatology, 1984