Choice Behavior of Drosophila Facing Contradictory Visual Cues
- 16 November 2001
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 294 (5546), 1543-1547
- https://doi.org/10.1126/science.1058237
Abstract
We studied the underlying neural mechanism of a simple choice behavior between competing alternatives in Drosophila . In a flight simulator, individual flies were conditioned to choose one of two flight paths in response to color and shape cues; after the training, they were tested with contradictory cues. Wild-type flies made a discrete choice that switched from one alternative to the other as the relative salience of color and shape cues gradually changed, but this ability was greatly diminished in mutant ( mbm 1 ) flies with miniature mushroom bodies or with hydroxyurea ablation of mushroom bodies. Thus, Drosophila genetics may be useful for elucidating the neural basis of choice behavior.This publication has 14 references indexed in Scilit:
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