In vitro evaluation of the effects of graphene platelets on glioblastoma multiforme cells
Open Access
- 1 January 2013
- journal article
- Published by Taylor & Francis Ltd in International Journal of Nanomedicine
- Vol. 8 (1), 413-420
- https://doi.org/10.2147/IJN.S39456
Abstract
Graphene is a single atom-thick material with exciting potential. It can be used in many fields, from electronics to biomedicine. However, little is known about its toxicity and biocompatibility. Herein, we report a study on the toxicity of graphene platelets (GPs) by examining the influence of GPs on the morphology, mortality, viability, membrane integrity, and type of cell death of U87 and U118 glioma cells. It was found that graphene is toxic to glioma cells, but it activated apoptosis only in the U118 cell line, without inducing necrosis, indicating the potential applicability of GP in anticancer therapy.This publication has 23 references indexed in Scilit:
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