Localization of the luminol‐dependent chemiluminescence reaction in human granulocytes
- 1 July 1989
- journal article
- phagocytosing
- Published by Wiley in Journal of Bioluminescence and Chemiluminescence
- Vol. 4 (1), 263-266
- https://doi.org/10.1002/bio.1170040137
Abstract
The granulocyte luminol-dependent chemiluminescence (CL) reaction is linked to the enzyme myeloperoxidase reacting with products of the respiratory burst activation. The results presented in this paper, show that the light generated in granulocytes originate both from intracellular and extracellular reactions; however, depending on the stimulus used the one or the other will dominate the activity measured. Furthermore, lysosomal fusion is proposed to be required for the intracellular CL reaction.Keywords
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