Acute myocardial infarction with no obstructive coronary atherosclerosis: mechanisms and management
Top Cited Papers
Open Access
- 18 December 2014
- journal article
- review article
- Published by Oxford University Press (OUP) in European Heart Journal
- Vol. 36 (8), 475-481
- https://doi.org/10.1093/eurheartj/ehu469
Abstract
Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment. We review pathogenesis, diagnosis, prognosis, and therapy of MINOCA and propose an algorithm for its management.Keywords
This publication has 43 references indexed in Scilit:
- Update on acute coronary syndromes: the pathologists' viewEuropean Heart Journal, 2012
- Safety of Coronary Reactivity Testing in Women With No Obstructive Coronary Artery Disease: Results From the NHLBI-Sponsored WISE (Women's Ischemia Syndrome Evaluation) StudyJACC: Cardiovascular Interventions, 2012
- Mechanisms of Myocardial Infarction in Women Without Angiographically Obstructive Coronary Artery DiseaseCirculation, 2011
- Reversible coronary microvascular dysfunction: a common pathogenetic mechanism in Apical Ballooning or Tako-Tsubo SyndromeEuropean Heart Journal, 2010
- Characterization and outcomes of women and men with non–ST-segment elevation myocardial infarction and nonobstructive coronary artery disease: Results from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines (CRUSADE) Quality Improvement InitiativeAmerican Heart Journal, 2009
- Are patients with angiographically near-normal coronary arteries who present as acute myocardial infarction actually safe?International Journal of Cardiology, 2009
- Coronary vasospasm as the underlying cause for chest pain in patients with PVB19 myocarditisHeart, 2008
- Do inherited prothrombotic factors have a role in myocardial infarction with normal coronary arteriogram?Journal of Internal Medicine, 1998
- Paradoxical Embolism — Thrombus in Transit through a Patent Foramen OvaleNew England Journal of Medicine, 1997
- Clinical characteristics and long-term prognosis of patients with variant angina. A comparative study between western and Japanese populationsInternational Journal of Cardiology, 1988