Expeditious Synthesis of Highly Substituted Indolizinones via a Palladium-Catalyzed Domino Sequence
- 5 May 2010
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 12 (11), 2500-2503
- https://doi.org/10.1021/ol1006778
Abstract
A direct one-pot approach to polysubstituted indolizinones from tertiary propargylic alcohols using a palladium-catalyzed domino process involving aminopalladation, reductive elimination, and 1,2-shift is described.Keywords
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