Missense Mutation in APOC3 within the C-terminal Lipid Binding Domain of Human ApoC-III Results in Impaired Assembly and Secretion of Triacylglycerol-rich Very Low Density Lipoproteins: EVIDENCE THAT ApoC-III PLAYS A MAJOR ROLE IN THE FORMATION OF LIPID PRECURSORS WITHIN THE MICROSOMAL LUMEN*
Open Access
- 5 August 2011
- journal article
- Published by Elsevier BV
- Vol. 286 (31), 27769-27780
- https://doi.org/10.1074/jbc.m110.203679
Abstract
No abstract availableThis publication has 37 references indexed in Scilit:
- Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemiaJournal of Lipid Research, 2010
- Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver DiseaseThe New England Journal of Medicine, 2010
- Nonsynonymous Mutations within APOB in Human Familial Hypobetalipoproteinemia: EVIDENCE FOR FEEDBACK INHIBITION OF LIPOGENESIS AND POSTENDOPLASMIC RETICULUM DEGRADATION OF APOLIPOPROTEIN BPublished by Elsevier BV ,2010
- Recent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretionNutrition & Metabolism, 2010
- The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with MitochondriaPublished by Elsevier BV ,2009
- A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent CardioprotectionScience, 2008
- Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver diseaseJCI Insight, 2007
- Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction NetworksGenome Research, 2003
- Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo.JCI Insight, 1986
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976