Predictors of First-Week Mortality in Patients with Acute Spontaneous Cerebellar Hemorrhage
- 21 August 2012
- journal article
- Published by Springer Science and Business Media LLC in The Cerebellum
- Vol. 12 (2), 165-170
- https://doi.org/10.1007/s12311-012-0410-6
Abstract
Cerebellar hemorrhage (CH) is considered a predictive factor for poor outcome after intracranial hemorrhage because of the high risk of brainstem compression. Hence, predictors of early mortality in patients with spontaneous CH are clinically valuable. However, the predictors of death within 7 days of CH onset have not yet been studied. In this study, 70 patients with acute spontaneous CH were retrospectively analyzed. The patients were divided into the first-week mortality group (n = 15, died within 7 days) and survival group (n = 55, survived at discharge). The association between first-week mortality and clinical characteristics was investigated using a multivariate logistic regression. The initial Glasgow coma scale (GCS) values (5.0 ± 2.8) in the first-week mortality group were significantly lower than those in the survival group (12.8 ± 3.3) (p < 0.001). Brainstem compression was indicative of first-week mortality (p < 0.001). GCS scores ≤8 (odds ratio, OR = 32.344, p = 0.003) and brainstem compression (OR = 14.417, p = 0.009) were strong predictors of first-week mortality in patients with CH. This is the first study showing that GCS scores ≤8 on arrival and brainstem compression are strong predictive factors for first-week mortality in patients with CH. These patients were about 32 and 14.5 times, respectively, more likely to die within 7 days.Keywords
This publication has 26 references indexed in Scilit:
- Serum C-reactive protein and lipid hydroperoxides in predicting short-term clinical outcome after spontaneous intracerebral hemorrhageJournal of Clinical Neuroscience, 2011
- Guidelines for the Management of Spontaneous Intracerebral Hemorrhage in AdultsStroke, 2007
- Hyperglycemia independently increases the risk of early death in acute spontaneous intracerebral hemorrhageJournal of the Neurological Sciences, 2007
- Admission blood glucose and short term survival in primary intracerebral haemorrhage: a population based studyJournal of Neurology, Neurosurgery & Psychiatry, 2005
- Long-Term Outcome after Spontaneous Cerebellar HaemorrhageEuropean Neurology, 2004
- The ICH ScoreStroke, 2001
- Rate of 24-hour blood pressure decline and mortality after spontaneous intracerebral hemorrhageCritical Care Medicine, 1999
- Predicting neurologic deterioration in patients with cerebellar hematomasNeurology, 1998
- Treatment of Hypertensive Cerebellar Hemorrhage–Surgical or Conservative Management?Neurosurgery, 1994
- Cerebellar hemorrhage and infarction.Stroke, 1982