fMRI mapping of a morphed continuum of 3D shapes within inferior temporal cortex
Open Access
- 4 March 2008
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences of the United States of America
- Vol. 105 (9), 3605-3609
- https://doi.org/10.1073/pnas.0712274105
Abstract
Here, we mapped fMRI responses to incrementally changing shapes along a continuous 3D morph, ranging from a head (“face”) to a house (“place”). The response to each shape was mapped independently by using single-stimulus imaging, and stimulus shapes were equated for lower-level visual cues. We measured activity in 2-mm samples across human inferior temporal cortex from the fusiform face area (FFA) (apparently selective for faces) to the parahippocampal place area (PPA) (apparently selective for places), testing for (i) incremental changes in the topography of FFA and PPA (predicted by the continuous-mapping model) or (ii) little or no response to the intermediate morphed shapes (predicted by the category model). Neither result occurred; instead, we found approximately linearly graded changes in the response amplitudes to graded-shape changes, without changes in topography—similar to visual responses in different lower-tier cortical areas.Keywords
This publication has 40 references indexed in Scilit:
- Object Category Structure in Response Patterns of Neuronal Population in Monkey Inferior Temporal CortexJournal of Neurophysiology, 2007
- Approximations of Shape Metrics and Application to Shape Warping and Empirical Shape StatisticsFoundations of Computational Mathematics, 2004
- Distributed and Overlapping Representations of Faces and Objects in Ventral Temporal CortexScience, 2001
- A Cortical Area Selective for Visual Processing of the Human BodyScience, 2001
- Representation of Perceived Object Shape by the Human Lateral Occipital ComplexScience, 2001
- Cortical Surface-Based AnalysisNeuroImage, 1999
- Cortical Surface-Based AnalysisNeuroImage, 1999
- Functional imaging of human visual recognitionCognitive Brain Research, 1996
- Neural correlates of category-specific knowledgeNature, 1996
- The protective effects of vitamin E on microcephaly in rats X-irradiated in utero: DNA, lipid peroxide and confronting cisternaeDevelopmental Brain Research, 1986