Tissue Quantification With Acoustic Radiation Force Impulse Imaging: Measurement Repeatability and Normal Values in the Healthy Liver
- 1 July 2010
- journal article
- Published by American Roentgen Ray Society in American Journal of Roentgenology
- Vol. 195 (1), 132-136
- https://doi.org/10.2214/ajr.09.3923
Abstract
OBJECTIVE. The purpose of this study was to describe the most reliable measurement procedure for acoustic radiation force impulse technology and to define the normal wave velocity values in a healthy liver. SUBJECTS AND METHODS. Twenty healthy volunteers underwent acoustic radiation force impulse imaging tissue quantification and were enrolled in this prospective study. All patients were examined by two independent operators at the same time. Twenty-four measurements per subject were obtained. Intraoperator and interoperator evaluations were performed. Statistical comparison of all mean data was performed with Student's t test. A value of p < 0.05 was considered significant. A comparative analysis was performed, and interclass correlation coefficients were calculated. RESULTS. The operators obtained 960 measurements. A statistically significant difference was found between the mean shear wave velocity values obtained by one operator deep in the right lobe of the liver and the values obtained on the surface of the right lobe (1.56 vs 1.90 m/s) and between the mean values obtained deep in the right lobe and those obtained deep in the left lobe (1.56 vs 1.84 m/s). The other operator had similar results. The distribution of all mean values obtained by both operators deep in the right hepatic lobe exhibited less dispersion (95% CI, 1.391–1.725) than those obtained on the surface (95% CI, 1.664–2.136). In 77.5% of cases, the shear wave speeds were between 1 and 2 m/s. No statistically significant difference was found in the comparisons performed on the right hepatic lobe by the two operators. The interclass correlation coefficient calculated for measurements deep in the right lobe was 0.87 (p < 0.0001). CONCLUSION. Acoustic radiation force impulse imaging quantification of hepatic tissue is more reproducible when applied to the deeper portion of the right lobe of the liver.Keywords
This publication has 32 references indexed in Scilit:
- Liver Fibrosis in Viral Hepatitis: Noninvasive Assessment with Acoustic Radiation Force Impulse Imaging versus Transient ElastographyRadiology, 2009
- A mechanical model to compute elastic modulus of tissues for harmonic motion imagingJournal of Biomechanics, 2008
- Regularization of tissue shear modulus reconstruction using strain varianceIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2008
- Viscoelastic property measurement in thin tissue constructs using ultrasoundIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2008
- Imaging and Estimation of Tissue Elasticity by UltrasoundUltrasound Quarterly, 2007
- Ultrasound-Based Transient Elastography for the Detection of Hepatic Fibrosis: Systematic Review and Meta-analysisClinical Gastroenterology and Hepatology, 2007
- Transient Elastography Using Impulsive Ultrasound Radiation Force: A Preliminary Comparison With Surface Palpation ElastographyJapanese Journal of Clinical Oncology, 2007
- Shear wave speed recovery using moving interference patterns obtained in sonoelastography experimentsThe Journal of the Acoustical Society of America, 2007
- Selected Methods for Imaging Elastic Properties of Biological TissuesAnnual Review of Biomedical Engineering, 2003
- Shear modulus imaging with 2-D transient elastographyIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2002