Effect of Acute and Chronic Physical Exercise on Patients with Periodic Leg Movements
- 1 January 2009
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Medicine & Science in Sports & Exercise
- Vol. 41 (1), 237-242
- https://doi.org/10.1249/mss.0b013e318183bb22
Abstract
Purpose: Nonpharmacological interventions may lead to an improvement in sleep quality. The objective of our study was to evaluate the effects of acute intensive exercise and chronic exercise on sleep patterns in patients with periodic leg movements (PLM). Methods: The study involved acute and chronic exercise. The acute intensive exercise group consisted of 22 volunteers who underwent a maximum effort test and a polysomnography (PSG) on the same night. The chronic exercise group included 11 patients who performed 72 physical training sessions undergoing three PSG studies on the night of sessions 1, 36, and 72. Blood samples were collected from both acute and chronic groups for β-endorphin dosage. Results: Our results showed that both forms of physical exercise lowered PLM levels. The acute physical exercise increased sleep efficiency, rapid eye movement (REM) sleep, and reduced wake after sleep onset, whereas the chronic physical exercise increased sleep efficiency, REM sleep, and reduced sleep latency. We also found a significant negative correlation between β-endorphin release after acute intensive exercise and PLM levels (r = −0.63). Conclusion: Physical exercise may improve sleep patterns and reduce PLM levels. The correlation between β-endorphin release after acute intensive exercise and PLM levels might be associated with the impact physical exercise has on the opiodergic system. We suggest that physical exercise may be a useful nonpharmacological treatment for PLM.This publication has 24 references indexed in Scilit:
- Exercise and Restless Legs Syndrome: A Randomized Controlled TrialThe Journal of the American Board of Family Medicine, 2006
- Comparison between dopaminergic agents and physical exercise as treatment for periodic limb movements in patients with spinal cord injurySpinal Cord, 2004
- Neuropathological examination suggests impaired brain iron acquisition in restless legs syndromeNeurology, 2003
- Reduction of periodic leg movement in individuals with paraplegia following aerobic physical exerciseSpinal Cord, 2002
- μ- and δ-Opioid Receptor Antagonists Reduce Levodopa-Induced Dyskinesia in the MPTP-Lesioned Primate Model of Parkinson's DiseaseExperimental Neurology, 2001
- Enhancement of natural immunity seen after voluntary exercise in rats. Role of central opioid receptorsLife Sciences, 2000
- Practice Parameters for the Treatment of Restless Legs Syndrome and Periodic Limb Movement DisorderSleep, 1999
- Treatment of periodic leg movements with a dopaminergic agonist in subjects with total spinal cord lesions.Spinal Cord, 1999
- Effect of RepeatedExperimental Neurology, 1999
- Incidence of periodic leg movements and of the restless legs syndrome during sleep following acute physical activity in spinal cord injury subjectsSpinal Cord, 1996