Rupture of membranes before the age of viability and birth after the age of viability: comparison of outcomes in a matched cohort study
Open Access
- 11 March 2010
- journal article
- research article
- Published by Springer Science and Business Media LLC in Journal of Perinatology
- Vol. 30 (10), 645-649
- https://doi.org/10.1038/jp.2010.11
Abstract
To compare composite adverse outcome rate of infants 7 days of PPROM that occurred before 24 weeks. Matched cohort consisted of infants born without PPROM (matched for GA, sex and admission date). Composite adverse outcome was assessed considering death or any of the following three severe morbidities (severe neurological injury, severe retinopathy of prematurity or chronic lung disease). The 29 cases had higher mean severity of illness score compared with 74 matched infants. Mean duration of ROM was 45 vs 2 days and mean GA at the ROM was 21 vs 27 weeks, respectively. Logistic regression confirmed significantly higher risk of composite adverse outcome rates for cases (69 vs 47%; P=0.02, adjusted odds ratio 4.0, 95% CI 1.2, 13.6). The survival rate for infants born at <32 weeks following PPROM at previable age has improved significantly; however, these infants had a higher rate of adverse composite neonatal outcome.Keywords
This publication has 29 references indexed in Scilit:
- Outcomes following prolonged preterm premature rupture of the membranesArchives of Disease in Childhood: Fetal & Neonatal, 2008
- Conservative management of preterm premature rupture of membranes between 18 and 23 weeks of gestation—Maternal and neonatal outcomeEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, 2006
- Predictors of perinatal survival in a cohort of pregnancies with severe oligohydramnios due to premature rupture of membranes at <26 weeks managed with serial amnioinfusionsEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, 2006
- Risk factors for previable premature rupture of membranes or advanced cervical dilation: A case control studyAmerican Journal of Obstetrics and Gynecology, 2006
- Preterm premature rupture of the membranes: diagnosis and managementClinics in Perinatology, 2004
- A New and Improved Population-Based Canadian Reference for Birth Weight for Gestational AgePEDIATRICS, 2001
- Survival and 2-year outcome with expectant management of second-trimester rupture of membranesObstetrics & Gynecology, 1998
- The CRIB (clinical risk index for babies) score: a tool for assessing initial neonatal risk and comparing performance of neonatal intensive care unitsThe Lancet, 1993
- Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with birth weights less than 1,500 gmThe Journal of Pediatrics, 1978
- Neonatal Necrotizing EnterocolitisAnnals of Surgery, 1978