In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity
- 8 November 2018
- journal article
- research article
- Published by Elsevier BV in Cell Stem Cell
- Vol. 23 (6), 806-819.e4
- https://doi.org/10.1016/j.stem.2018.10.018
Abstract
No abstract availableFunding Information
- Chinese Academy of Sciences (XDA16020201)
- Shanghai Science and Technology Committee (16JC1400202, 15JC1400200)
- National Science Foundation of China (31630044, 31601186, 31801228, 81471948)
- External Cooperation Program of BIC
- CSIRO-Chinese Academy of Science (153D31KYSB20150085, 153D31KYSB20160247)
- China Postdoctoral Science Foundation (2017M620174, 2018T110412)
This publication has 41 references indexed in Scilit:
- Cell fate conversion: Direct induction of hepatocyte‐like cells from fibroblastsJournal of Cellular Biochemistry, 2012
- Signals and Cells Involved in Regulating Liver RegenerationCells, 2012
- Hypoxia suppresses conversion from proliferative arrest to cellular senescenceProceedings of the National Academy of Sciences of the United States of America, 2012
- The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functionalBiochemical and Biophysical Research Communications, 2011
- Human hepatocyte transplantation: current experience and future challengesNature Reviews Gastroenterology & Hepatology, 2010
- Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearanceProceedings of the National Academy of Sciences of the United States of America, 2009
- Microscale culture of human liver cells for drug developmentNature Biotechnology, 2007
- Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− miceNature Biotechnology, 2007
- Oxygen sensitivity severely limits the replicative lifespan of murine fibroblastsNature, 2003
- Recent Advances in Human Hepatocyte Culture SystemsBiochemical and Biophysical Research Communications, 2000