Metal-Catalyzed Decarboxylative C–H Functionalization
Top Cited Papers
- 7 March 2017
- journal article
- review article
- Published by American Chemical Society (ACS) in Chemical Reviews
- Vol. 117 (13), 8864-8907
- https://doi.org/10.1021/acs.chemrev.6b00516
Abstract
C-H bond activation and decarboxylation are two significant processes in organic synthesis. The combination of these processes provides a novel synthetic strategy, that is, decarboxylative C-H bond functionalization. Considerable attention has been focused on such an active research field. This review offers an overview of the utility of decarboxylative C-H bond functionalization in the synthesis of various organic compounds, such as styrenes, chalcones, biaryls, and heterocycles, covering most of the recent advances of the decarboxylative functionalization of Csp-H, Csp-H, and Csp-H bonds, as well as their scopes, limitations, practical applications, and synthetic potentials.Keywords
Funding Information
- Sun Yat-sen University
- Natural Science Foundation of Chongqing (cstc2016jcyjA0008)
- CAS-SAFEA International Partnership Program for Creative Research Teams
- National Natural Science Foundation of China (21302220, 21332001, 21431008, u1505242)
- State Key Laboratory of Structural Chemistry (20150009)
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