Retest positive for SARS‐CoV‐2 RNA of “recovered” patients with COVID‐19: Persistence, sampling issues, or re‐infection?

Abstract
“Re‐test Positive” for SARS‐CoV‐2 from “recovered” COVID‐19 has been reported and raised several important questions for this novel coronavirus and COVID‐19 disease. In this commentary, we discussed several questions: 1. Can SARS‐CoV‐2 re‐infect the individuals who recovered from COVID‐19? This question is also associated with other questions: whether or not SARS‐CoV‐2 infection induces protective reaction or neutralized antibody? Will SARS‐CoV‐2 vaccines work? 2. Why could some recovered COVID‐19 patients be re‐tested positive for SARS‐CoV‐2 RNA? 3. Are some recovered COVID‐19 patients with re‐testing positive for SARS‐CoV‐2 RNA infectious? 4. How should the COVID‐19 patients with re‐test positive for SARS‐CoV‐2 be managed?