The role of calcium metabolism dysregulation in the pathogenesis of cardiovascular diseases
Open Access
- 8 September 2019
- journal article
- Published by Silicea - Poligraf, LLC in Russian Journal of Cardiology
- No. 9,p. 78-85
- https://doi.org/10.15829/1560-4071-2019-9-78-85
Abstract
The review presents data on the causes of dysregulation of calcium metabolism and its association with the main elements of the cardiovascular continuum. Particular attention was paid to its role in the regulation of endothelial function, systemic inflammation, myocardial contractility, lipid and carbohydrate metabolism, the disruption of which determines the initiation and progression of diseases such as essential hypertension and chronic heart failure. We also systematized data on the role and methods of calcium dysmetabolism correcting in the prevention and treatment of these pathologies.Keywords
This publication has 42 references indexed in Scilit:
- RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectivesJournal of Experimental & Clinical Cancer Research, 2019
- Vitamin D Deficiency, Supplementation, and Cardiovascular HealthCritical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 2017
- Renal Control of Calcium, Phosphate, and Magnesium HomeostasisClinical Journal of the American Society of Nephrology, 2015
- Calcium Supplements and Cardiovascular DiseaseAmerican Journal of Lifestyle Medicine, 2013
- Calcium-sensing in the kidneyCurrent Opinion in Nephrology and Hypertension, 2013
- New insights in regulation of calcium homeostasisCurrent Opinion in Nephrology and Hypertension, 2013
- The role of the gastrointestinal tract in calcium homeostasis and bone remodelingOsteoporosis International, 2013
- Deficiency of the Calcium-Sensing Receptor in the Kidney Causes Parathyroid Hormone–Independent HypocalciuriaJournal of the American Society of Nephrology, 2012
- The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to KnowJournal of Clinical Endocrinology & Metabolism, 2011
- Development and progression of secondary hyperparathyroidism in chronic kidney disease: lessons from molecular geneticsKidney International, 2008