Testosterone Deficiency and Replacement in Older Men
- 8 July 2010
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 363 (2), 189-191
- https://doi.org/10.1056/nejme1006197
Abstract
It is now clear that men have gradual declines in average serum testosterone levels as they age. These decreases begin by middle age and continue into old age.1,2 Although the decreases are substantial in many men, they are quite variable. Some men, even in old age, maintain serum testosterone levels similar to those of healthy young men.Many of the physical and behavioral changes that occur in men as they age are similar to those that occur in younger men with hypogonadism. These changes include decreases in muscle mass, strength, bone mass, and sexual function and increases in body . . .Keywords
This publication has 8 references indexed in Scilit:
- Identification of Late-Onset Hypogonadism in Middle-Aged and Elderly MenNew England Journal of Medicine, 2010
- Adverse Events Associated with Testosterone AdministrationNew England Journal of Medicine, 2010
- Adverse Effects of Testosterone Therapy in Adult Men: A Systematic Review and Meta-AnalysisJournal of Clinical Endocrinology & Metabolism, 2010
- Testosterone Therapy in Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice GuidelineJournal of Clinical Endocrinology & Metabolism, 2010
- Investigation, Treatment, and Monitoring of Late‐Onset Hypogonadism in Males: ISA, ISSAM, EAU, EAA, and ASA RecommendationsJournal of Andrology, 2009
- Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum TJournal of Clinical Endocrinology & Metabolism, 2005
- Age Trends in the Level of Serum Testosterone and Other Hormones in Middle-Aged Men: Longitudinal Results from the Massachusetts Male Aging StudyJournal of Clinical Endocrinology & Metabolism, 2002
- Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy MenJournal of Clinical Endocrinology & Metabolism, 2001