Incidence and survival of squamous cell carcinoma of the tongue in Scandinavia, with special reference to young adults
Open Access
- 16 July 2002
- journal article
- research article
- Published by Wiley in International Journal of Cancer
- Vol. 101 (1), 95-99
- https://doi.org/10.1002/ijc.10577
Abstract
In several countries, increased incidence of squamous cell carcinoma (SCC) of the tongue in young adults has been suspected during the last decades. Some reports indicate a lower survival rate for young patients compared to older patients. In other reports, there has not been any considerable difference in survival when comparing young adults to older patients, whereas some authors have shown better survival for young adults. This disease is rare in young adults, and early reports were based on comparable small numbers and selected patients. Our aim was first to perform a population‐based study to determine if an increased incidence in SCC of the tongue could be verified in a larger population comprising the Scandinavian countries Denmark, Finland, Sweden and Norway. A second aim was to determine survival rates for young adults compared to older patients. The material was based on the annual cancer incidence and survival reports from the Scandinavian cancer registries. The study period was 1960–1994. During that period, 5,024 SCCs of the tongue were reported. Of these, 276 (5.5%) were young adults (20–39 years). The incidence increased at all ages except for women 65–79 years old. The increase was most pronounced in young adults: 0.06–0.32 for men and 0.03–0.19 for women, counted by 100,000 person‐years. Relative survival was significantly better for young adults compared to older patients.Keywords
Funding Information
- Swedish Cancer Society (4478-B00-01PAB, 1304-B00-14XCC)
- King Gustaf V Jubilee Fund (00:530)
- Swedish Department of Education
This publication has 30 references indexed in Scilit:
- Human Papillomavirus Infection as a Risk Factor for Squamous-Cell Carcinoma of the Head and NeckNew England Journal of Medicine, 2001
- Cancer of the Mobile Tongue in Finland: Increasing Incidence, but Improved SurvivalActa Oncologica, 1999
- Genetic Susceptibility to Head and Neck Squamous Cell CarcinomaJNCI Journal of the National Cancer Institute, 1996
- Head and neck cancer in NorwayAPMIS, 1995
- Oral tongue cancer in young adults less than 40 years of age: Rationale for aggressive therapyHead & Neck, 1994
- Association between bleomycin genotoxicity and non-constitutional risk factors for head and neck cancerCancer Letters, 1993
- Squamous carcinoma of the head and neck in the young adultClinical Otolaryngology, 1992
- INCREASING INCIDENCE OF CANCER OF THE TONGUE IN THE UNITED STATES AMONG YOUNG ADULTSThe Lancet, 1987
- Rising Mortality from Cancer of the Tongue in Young White MalesNew England Journal of Medicine, 1986
- A computer program package for relative survival analysisComputer Programs in Biomedicine, 1985