Waist-to-Height: Cutoff Matters in Predicting Metabolic Syndrome in Mexican Children
- 1 June 2011
- journal article
- Published by Mary Ann Liebert Inc in Metabolic Syndrome and Related Disorders
- Vol. 9 (3), 183-190
- https://doi.org/10.1089/met.2010.0116
Abstract
Body-mass index (BMI), waist circumference (WC), and, recently, waist-to-height ratio (WHtR) have been proposed as clinical indexes to identify children at cardiometabolic risk. The aim was to identify the usefulness of WHtR cutoffs, WC, and BMI as predictors of metabolic syndrome in Mexican children, according to BMI z-scores, and the severity of obesity to cardiometabolic risk factors and metabolic syndrome. This was a cross-sectional study of 214 overweight/obese and 47 normal-weight Mexican children 6-12 years old. Children were divided in groups according to BMI z-scores. Anthropometric and biochemical measurements were determined. Receiver-operating characteristic (ROC) curves and areas under the curves were calculated to compare the abilities of the anthropometric measurements to predict metabolic syndrome. The overall prevalence of metabolic syndrome was 23.3%, ranging from 11.0% in the overweight group to 73.9% in the severely obese one. Children with metabolic syndrome had significantly higher WHtR, WC, BMI, percentage of body fat, triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), systolic and diastolic blood pressure, and lower high-density lipoprotein cholesterol (HDL-C). A WHtR cutoff point of 0.59 from the ROC curve was identified as strong predictor of metabolic syndrome in our population, whereas a cutoff of 0.5 showed very poor specificity (22.7%). WC predicted metabolic syndrome as well. Cutoff values for WHtR make a difference in predicting metabolic syndrome. A cutoff of 0.59 for WHtR strongly predicted metabolic syndrome; it might be a simpler to use screening tools and counters for short people. Further studies are required to determine the cutoff points for an accurate prediction, because there are few in children and none in Mexico.Keywords
This publication has 36 references indexed in Scilit:
- Prevalence of the Metabolic Syndrome Among U.S. Adolescents Using the Definition From the International Diabetes FederationDiabetes Care, 2008
- An overview of pediatric obesityPediatric Diabetes, 2007
- Metabolic Syndrome in Childhood Predicts Adult Cardiovascular Disease 25 Years Later: The Princeton Lipid Research Clinics Follow-up StudyPediatrics, 2007
- Waist Circumference Identifies Primary School Children with Metabolic Syndrome AbnormalitiesDiabetes Technology & Therapeutics, 2007
- Childhood Overweight and Cardiovascular Disease Risk Factors: The National Heart, Lung, and Blood Institute Growth and Health StudyThe Journal of Pediatrics, 2007
- Crossvalidation of anthropometry against magnetic resonance imaging for the assessment of visceral and subcutaneous adipose tissue in childrenInternational Journal of Obesity, 2005
- Waist circumference as a predictor of cardiovascular and metabolic risk factors in obese girlsEuropean Journal of Clinical Nutrition, 2003
- Obesity, Insulin Resistance, Diabetes, and Cardiovascular Risk in ChildrenCirculation, 2003
- Waist circumference for the screening of the metabolic syndrome in childrenActa Paediatrica, 2002
- Utility of Different Measures of Body Fat Distribution in Children and AdolescentsAmerican Journal of Epidemiology, 2000