Sexual Intercourse and Risk of Symptomatic Urinary Tract Infection in Post-Menopausal Women
- 12 February 2008
- journal article
- Published by Springer Science and Business Media LLC in Journal of General Internal Medicine
- Vol. 23 (5), 595-599
- https://doi.org/10.1007/s11606-008-0535-y
Abstract
Sexual intercourse increases the risk of symptomatic urinary tract infections (UTI) in young women, but its role among post-menopausal women is unclear. To determine whether recent sexual intercourse, as documented by daily diaries, is associated with an increased risk of symptomatic UTI in post-menopausal women. A 2-year prospective cohort study conducted from 1998 to 2002. One thousand and seventeen randomly selected post-menopausal women enrolled at Group Health Cooperative (GHC), a Washington State HMO. Women were asked to enter daily diary information on vaginal intercourse, medication use, and genito-urinary symptoms. The outcome of interest, symptomatic UTI, was defined as a positive urine culture ≥105 CFU/mL of a uropathogen and the presence of ≥2 acute urinary symptoms. Nine hundred thirteen women returned diaries and were included in this study. Seventy-eight women experienced 108 symptomatic UTIs, and 361 (40%) reported sexual intercourse in their diaries. There was an increased hazard for UTI 2 calendar days after the reporting of sexual intercourse in the diaries (adjusted hazard ratio [HR], 3.42, 95% CI 1.49–7.80), while there was no evidence for an increased hazard associated with intercourse at other times. When the UTI criterion was relaxed from ≥105 CFU/mL to ≥104 CFU/mL, adding 9 UTI events to the analysis, the HR for UTI 2 days after intercourse changed slightly to 3.26 (95% CI 1.43–7.43). Our data suggest that, as with younger women, recent sexual intercourse is strongly associated with incident UTI in generally healthy post-menopausal women.Keywords
This publication has 29 references indexed in Scilit:
- A Study of Sexuality and Health among Older Adults in the United StatesNew England Journal of Medicine, 2007
- Pregnancy Outcomes following Hospitalization for Motor Vehicle Crashes in Washington State from 1989 to 2001American Journal of Epidemiology, 2005
- Sexual Behavior of Older WomenSexually Transmitted Diseases, 2003
- Diabetes and the Risk of Acute Urinary Tract Infection Among Postmenopausal WomenDiabetes Care, 2002
- Urinary tract infections in postmenopausal women: effect of hormone therapy and risk factorsPublished by Ovid Technologies (Wolters Kluwer Health) ,2001
- Urinary tract infection among women aged 40 to 65Journal of Clinical Epidemiology, 2001
- Recurrent urinary tract infection in womenInternational Journal of Antimicrobial Agents, 2001
- Risk Factors for Recurrent Urinary Tract Infection in Young WomenThe Journal of Infectious Diseases, 2000
- Comparisons of the Costs and Quality of Norms for the SF-36 Health Survey Collected by Mail Versus Telephone Interview: Results From a National SurveyMedical Care, 1994
- The Association of Urinary Tract Infection with Sexual IntercourseThe Journal of Infectious Diseases, 1982