Routes of drug administration: uses and adverse effects
- 1 December 2008
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Adverse Drug Reaction Bulletin
- Vol. &NA; (253), 971-974
- https://doi.org/10.1097/fad.0b013e328329bb21
Abstract
Drugs are effective only if they reach their site of action. This is usually achieved by oral administration, but other routes are possible. Here I describe the uses and characteristic adverse effects of commonly used routes of administration. In this part I deal with intramuscular and subcutaneous injection and in part 2 other routes.Keywords
This publication has 27 references indexed in Scilit:
- Gold Standards in PharmacovigilanceDrug Safety, 2007
- SOFT-TISSUE SARCOMA ARISING FROM A TISSUE NECROSIS CAUSED BY AN INTRAMUSCULAR INJECTION OF DICLOFENACPlastic and Reconstructive Surgery, 2003
- Pediatric Use of Intravenous and Intramuscular Phenytoin: Lessons LearnedJournal of Child Neurology, 1998
- Comparative absorption kinetics of intramuscular midazolam and diazepamCanadian Journal of Anesthesia/Journal canadien d'anesthésie, 1996
- Intramuscular Injection Abscess — Past Lessons RelearnedNew England Journal of Medicine, 1991
- Intramuscular or Intralipomatous Injections?New England Journal of Medicine, 1982
- Absorption of oral and intramuscular chlordiazepoxideEuropean Journal of Clinical Pharmacology, 1978
- The Effect on Serum Enzymes of Intramuscular Injections of Digoxin, Bumetanide, Pentazocine and Isotonic Sodium ChlorideActa Medica Scandinavica, 1976
- Plasma digoxin after parenteral administration Local reaction after intramuscular injectionClinical Pharmacology & Therapeutics, 1974
- ROUTINE SKIN PREPARATION BEFORE INJECTION: An Unnecessary ProcedureThe Lancet, 1969