Needle Temperature Effect on Pain Ratings After Injection
- 1 March 2008
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in The Clinical Journal of Pain
- Vol. 24 (3), 260-264
- https://doi.org/10.1097/ajp.0b013e31816111c0
Abstract
Little research regarding appropriate immunization administration technique for adults has been carried out. Pain is a leading cause of self-deferral from immunizations. The purpose of this study was to determine whether administering intramuscular injections using cold needles would decrease patients' perceived pain and have an effect on the immune response elicited by the vaccine. Eighty participants received an injection of influenza vaccine in 1 arm and a saline injection in the other using a cold or room temperature needle in a double-blind fashion assigned at random. Participants rated their pain after each injection using a standard visual pain scale bounded by no pain and most painful injection ever. Vaccine antibody response was measured using hemagglutination inhibition assays. Overall, pain scores after influenza vaccine administration were quite low (34.2+/-2.5 mm). The mean pain score for influenza vaccine was not different using cold or room temperature needles (cold 32.2 mm+/-3.20 vs. room temperature 36.0 mm+/-3.80; t=0.76; P=0.450). The mean pain scores for saline injections did not differ (room temperature 23.7 mm+/-3.19 vs. cold 25.2+/-2.95; t=-0.34; P=0.73). Individuals receiving injections with cold needles had less bruising (0/40 vs. 5/40; P<0.02) at the injection site, but incidences of pain and erythema were similar. The use of cold needles for vaccine administration had no effect on antibody response. Pain after influenza vaccine administration is generally mild. Use of cold needles may not be worth pursuing for injections associated with mild pain. However, it may be worthwhile to explore using cold needles as an analgesic with more painful injections.Keywords
This publication has 19 references indexed in Scilit:
- Pain Reduction During Pediatric Immunizations: Evidence-Based Review and RecommendationsPEDIATRICS, 2007
- Topical vapocoolant quickly and effectively reduces vaccine-associated pain: results of a randomized, single-blinded, placebo-controlled study.Journal of Travel Medicine, 2006
- Optimal technique for intramuscular injection of infants and toddlers: a randomised trialThe Medical Journal of Australia, 2005
- Effect of Influenza Immunization on CYP3A4 Activity In VivoThe Journal of Clinical Pharmacology, 2003
- Comparison of the safety, tolerability, and immunogenicity of a MF59-adjuvanted influenza vaccine and a non-adjuvanted influenza vaccine in non-elderly adultsVaccine, 2003
- Comparative study of distraction versus topical anesthesia for pediatric pain management during immunizations.Health Psychology, 1999
- Determination of Deltoid Fat Pad ThicknessJAMA, 1997
- Syncope After ImmunizationArchives of Pediatrics & Adolescent Medicine, 1997
- Effect of anatomic injection site, age and smoking on the immune response to hepatitis B vaccinationVaccine, 1989
- Characterization of the Immune Response to Trivalent Influenza Vaccine in Elderly MenJournal of the American Geriatrics Society, 1987