Beauvericin, a Bioactive Compound Produced by Fungi: A Short Review
Open Access
- 23 February 2012
- Vol. 17 (3), 2367-2377
- https://doi.org/10.3390/molecules17032367
Abstract
Beauvericin is a cyclic hexadepsipeptide mycotoxin, which has insecticidal, antimicrobial, antiviral and cytotoxic activities. It is a potential agent for pesticides and medicines. This paper reviews the bioactivity, fermentation and biosynthesis of the fungal product beauvericin.This publication has 47 references indexed in Scilit:
- Modeling of Fusarium redolens Dzf2 mycelial growth kinetics and optimal fed-batch fermentation for beauvericin productionJournal of Industrial Microbiology & Biotechnology, 2010
- A beauvericin hot spot in the genus IsariaMycological Research, 2009
- Enhanced beauvericin production with in situ adsorption in mycelial liquid culture of Fusarium redolens Dzf2Process Biochemistry, 2009
- Development of a LC-MS/MS Method for the Analysis of Enniatins and Beauvericin in Whole Fresh and Ensiled MaizeJournal of Agricultural and Food Chemistry, 2008
- High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infectionsProceedings of the National Academy of Sciences of the United States of America, 2007
- Search for Cell Motility and Angiogenesis Inhibitors with Potential Anticancer Activity: Beauvericin and Other Constituents of Two Endophytic Strains of Fusarium oxysporumJournal of Natural Products, 2007
- Induction of calcium influx from extracellular fluid by beauvericin in human leukemia cellsBiochemical and Biophysical Research Communications, 2006
- Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cellsCancer Letters, 2005
- Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calciumCancer Letters, 2004
- Nonribosomal biosynthesis of peptide antibioticsJBIC Journal of Biological Inorganic Chemistry, 1990