Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors
- 15 November 2006
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry Letters
- Vol. 16 (22), 5773-5777
- https://doi.org/10.1016/j.bmcl.2006.08.078
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolaseBioorganic & Medicinal Chemistry Letters, 2006
- Development of a high-throughput screen for soluble epoxide hydrolase inhibitionAnalytical Biochemistry, 2006
- Human soluble epoxide hydrolase: Structural basis of inhibition by 4‐(3‐cyclohexylureido)‐carboxylic acidsProtein Science, 2006
- TRPV4 Forms a Novel Ca 2+ Signaling Complex With Ryanodine Receptors and BK Ca ChannelsCirculation Research, 2005
- Modulation of the Ca 2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular EndotheliumCirculation Research, 2005
- EPOXIDE HYDROLASES: Mechanisms, Inhibitor Designs, and Biological RolesAnnual Review of Pharmacology and Toxicology, 2005
- Optimization of Amide-Based Inhibitors of Soluble Epoxide Hydrolase with Improved Water SolubilityJournal of Medicinal Chemistry, 2005
- Design, Synthesis, and Biological Activity of 1,3-Disubstituted Ureas as Potent Inhibitors of the Soluble Epoxide Hydrolase of Increased Water SolubilityJournal of Medicinal Chemistry, 2004
- Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channelsNature, 2003
- Cytosolic epoxide hydrolaseChemico-Biological Interactions, 1988