New method for 3D parametric visualization of contrast-enhanced pulmonary perfusion MRI data
Open Access
- 18 August 2007
- journal article
- research article
- Published by Springer Science and Business Media LLC in European Radiology
- Vol. 18 (2), 291-297
- https://doi.org/10.1007/s00330-007-0742-7
Abstract
Three-dimensional (3D) dynamic contrast-enhanced magnetic resonance imaging (3D DCE-MRI) has been proposed for the assessment of regional perfusion. The aim of this work was the implementation of an algorithm for a 3D parametric visualization of lung perfusion using different cutting planes and volume rendering. Our implementation was based on 3D DCE-MRI data of the lungs of five patients and five healthy volunteers. Using the indicator dilution theory, the regional perfusion parameters, tissue blood flow, blood volume and mean transit time were calculated. Due to the required temporal resolution, the volume elements of dynamic MR data sets show a reduced spatial resolution in the z-direction. Therefore, perfusion parameter volumes were interpolated. Linear interpolation and a combination of linear and nearest-neighbor interpolation were evaluated. Additionally, ray tracing was applied for 3D visualization. The linear interpolation algorithm caused interpolation errors at the lung borders. Using the combined interpolation, visualization of perfusion information in arbitrary cutting planes and in 3D using volume rendering was possible. This facilitated the localization of perfusion deficits compared with the coronal orientated source data. The 3D visualization of perfusion parameters using a combined interpolation algorithm is feasible. Further studies are required to evaluate the additional benefit from the 3D visualization.Keywords
This publication has 13 references indexed in Scilit:
- Contrast-enhanced 3D MRI of lung perfusion in children with cystic fibrosis—initial resultsEuropean Radiology, 2006
- The incorporation of SPECT functional lung imaging into inverse radiotherapy planning for non-small cell lung cancerRadiotherapy and Oncology, 2005
- Regional Lung Perfusion: Assessment with Partially Parallel Three-dimensional MR ImagingRadiology, 2004
- Quantitative Analysis of Pulmonary Perfusion using Time-Resolved Parallel 3D MRI - Initial resultsRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2004
- Quantification of renal perfusion abnormalities using an intravascular contrast agent (part 2): Results in animals and humans with renal artery stenosisMagnetic Resonance in Medicine, 2003
- Generalized autocalibrating partially parallel acquisitions (GRAPPA)Magnetic Resonance in Medicine, 2002
- Assessment of hepatic perfusion parameters with dynamic MRIMagnetic Resonance in Medicine, 2001
- Quantitative assessment of pulmonary perfusion with dynamic contrast-enhanced MRIMagnetic Resonance in Medicine, 1999
- High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: Experimental comparison and preliminary resultsMagnetic Resonance in Medicine, 1996
- Pulmonary perfusion: Qualitative assessment with dynamic contrast‐enhanced MRI using ultra‐short TE and inversion recovery turbo FLASHMagnetic Resonance in Medicine, 1996