Increased Turnover of Cerebral Norepinephrine during Rebound of Paradoxical Sleep in the Rat

Abstract

Changes in turnover of cerebral norepinephrine, as measured after intracisternal administration of the H³ amine, have been studied in rats during selective paradoxical sleep deprivation and its following rebound. Experiments were performed under neurophysiological control. A marked increase of turnover of norepinephrine is associated with the augmentation of paradoxical sleep characteristic of the rebound period.