Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes
Open Access
- 1 January 2010
- journal article
- Published by Elsevier BV in Molecular Therapy
- Vol. 18 (1), 181-187
- https://doi.org/10.1038/mt.2009.207
Abstract
No abstract availableKeywords
Funding Information
- National Institute of Biomedical Innovation
- Takeda Science Foundation
- Ministry of Education, Culture, Sports, Science and Technology
This publication has 29 references indexed in Scilit:
- The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activitiesNature Medicine, 2008
- Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA TargetsCell, 2005
- Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancersProceedings of the National Academy of Sciences of the United States of America, 2004
- DAVID: Database for Annotation, Visualization, and Integrated DiscoveryGenome Biology, 2003
- In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancerClinical & Experimental Metastasis, 2003
- Targeting the Kinesin Eg5 to Monitor siRNA Transfection in Mammalian CellsBioTechniques, 2002
- Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaProceedings of the National Academy of Sciences of the United States of America, 2002
- Loss of heterozygosity at 13q14 and 13q21 in high grade, high stage prostate cancerThe Prostate, 2001
- KEGG: Kyoto Encyclopedia of Genes and GenomesNucleic Acids Research, 2000
- Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv).1992