Novel Indolyl Aryl Sulfones Active against HIV-1 Carrying NNRTI Resistance Mutations: Synthesis and SAR Studies
- 8 May 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 46 (12), 2482-2493
- https://doi.org/10.1021/jm0211063
Abstract
No abstract availableKeywords
This publication has 8 references indexed in Scilit:
- The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infectionAntiviral Research, 1998
- Synthesis and Biological Evaluation of 5H-Indolo [3,2-b][1,5]Benzothiazepine Derivatives, Designed as Conformationally Constrained Analogues of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitor L-737,126Antiviral Chemistry and Chemotherapy, 1998
- 2-Sulfonyl-4-chloroanilino Moiety: A Potent Pharmacophore for the Anti-Human Immunodeficiency Virus Type 1 Activity of Pyrrolyl Aryl SulfonesJournal of Medicinal Chemistry, 1996
- Synthesis of Pyrryl Aryl Sulfones Targeted at the HIV‐1 Reverse TranscriptaseArchiv der Pharmazie, 1995
- Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptaseAntimicrobial Agents and Chemotherapy, 1993
- Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compoundsJournal of Virological Methods, 1988
- Pyrido[2,3-d]pyrimidines. The synthesis of the 5-deaza analogs of aminopterin, methotrexate, folic acid, and N10-methylfolic acidThe Journal of Organic Chemistry, 1982
- Alkyl and aryl sulfenimidesThe Journal of Organic Chemistry, 1969