Consumption of dairy products and the risk of breast cancer: a review of the literature
Open Access
- 1 July 2004
- journal article
- review article
- Published by Elsevier BV in The American Journal of Clinical Nutrition
- Vol. 80 (1), 5-14
- https://doi.org/10.1093/ajcn/80.1.5
Abstract
Differences in eating patterns and breast cancer rates across countries suggest that several dietary components, including dairy products, could affect breast cancer risk. However, dairy products are a diverse food group in terms of the factors that could potentially influence risk. Some dairy products, such as whole milk and many types of cheese, have a relatively high saturated fat content, which may increase risk. Moreover, milk products may contain contaminants such as pesticides, which have carcinogenic potential, and growth factors such as insulin-like growth factor I, which have been shown to promote breast cancer cell growth. In contrast, the calcium and vitamin D contents of dairy products have been hypothesized to reduce breast cancer risk. We reviewed the current epidemiologic literature on the relation between dairy product intakes and breast cancer risk, focusing primarily on the results of cohort and case-control studies. Most of the studies reviewed showed no consistent pattern of increased or decreased breast cancer risk with a high consumption of dairy products as a whole or when broken down into high-fat and low-fat dairy products, milk, cheese, or butter. Measurement error may have attenuated any modest association with dairy products. The available epidemiologic evidence does not support a strong association between the consumption of milk or other dairy products and breast cancer risk.Keywords
This publication has 77 references indexed in Scilit:
- Cancer Statistics, 2002CA: A Cancer Journal for Clinicians, 2002
- Global cancer statistics in the year 2000The Lancet Oncology, 2001
- Prevention of N-Methyl-N-Nitrosourea-Induced Mammary Carcinogenesis in Rats by 1alpha-Hydroxyvitamin D5JNCI Journal of the National Cancer Institute, 2000
- Role of the Insulin-Like Growth Factor Family in Cancer Development and ProgressionJNCI Journal of the National Cancer Institute, 2000
- Global cancer statisticsCA: A Cancer Journal for Clinicians, 1999
- A case-control study of breast cancer among Japanese women: with special reference to family history and reproductive and dietary factorsBreast Cancer Research and Treatment, 1992
- Patterns of milk consumption and risk of cancerNutrition and Cancer, 1990
- Dietary factors and the risk of breast cancerNutrition and Cancer, 1987
- The Calcium Messenger SystemNew England Journal of Medicine, 1986
- The Calcium Messenger SystemNew England Journal of Medicine, 1986