MRI-Based Selection for Intra-Arterial Stroke Therapy
- 1 June 2009
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Stroke
- Vol. 40 (6), 2046-2054
- https://doi.org/10.1161/strokeaha.108.541656
Abstract
Background and Purpose— Recent studies demonstrate that an acute diffusion-weighted imaging lesion volume >70 cm 3 predicts poor outcome in patients with stroke. We sought to determine if this threshold could identify patients treated with intra-arterial therapy who would do poorly despite reperfusion. In patients with initial infarcts 70 cm 3 , all had poor outcomes despite a 50% recanalization rate with mean infarct growth of 114 cm 3 . These patients also had the largest mean transit time volumes ( P 3 who recanalized early had the best clinical outcomes ( P P 3 . Conclusion— This study supports the use of an acute diffusion-weighted imaging lesion volume threshold as an imaging selection criterion for intra-arterial therapy. It also confirms the importance of early reperfusion in selected patients.This publication has 30 references indexed in Scilit:
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