Spontaneous reversion of a lineage switch following an initial blinatumomab-induced ALL-to-AML switch in MLL-rearranged infant ALL
Open Access
- 13 June 2018
- journal article
- research article
- Published by American Society of Hematology in Blood Advances
- Vol. 2 (12), 1382-1385
- https://doi.org/10.1182/bloodadvances.2018018093
Abstract
A case of MLL-rearranged leukemia that rapidly adapts to immunological stimuli illustrating the high plasticity of this phenotype.Keywords
This publication has 18 references indexed in Scilit:
- Lineage switch under blinatumomab treatment of relapsed common acute lymphoblastic leukemia without MLL rearrangementPediatric Blood & Cancer, 2017
- Updates in the biology and therapy for infant acute lymphoblastic leukemiaCurrent Opinion in Pediatrics, 2017
- CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticityNature Communications, 2016
- Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapyBlood, 2016
- Lineage Switch in MLL‐Rearranged Infant Leukemia Following CD19‐Directed TherapyPediatric Blood & Cancer, 2016
- Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 ImmunotherapyCancer Discovery, 2015
- Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocolLeukemia, 2015
- Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapyBlood, 2013
- Lineage switch in childhood acute leukemia: An unusual event with poor outcomeAmerican Journal of Hematology, 2012
- Interleukin 6 induces myeloid differentiation of a human biphenotypic leukemic cell lineLeukemia Research, 1992