The apatite formation ability of CaF 2 doping tricalcium silicates in simulated body fluid
- 30 June 2009
- journal article
- Published by IOP Publishing in Biomedical Materials
- Vol. 4 (4), 045005
- https://doi.org/10.1088/1748-6041/4/4/045005
Abstract
The purpose of this study was to investigate the effects of CaF(2) on the apatite formation ability of tricalcium silicates (Ca(3)SiO(5), C(3)S) and the mechanism of apatite formation on C(3)S pastes. Different amounts of CaF(2) (0, 1, 2 and 3 wt%) were mixed in the raw materials during the synthesis process of C(3)S. The apatite formation ability of the CaF(2) doping C(3)S was examined by soaking the one-day setting pastes in simulated body fluid (SBF). The fluoride concentrations, pH values, structural and morphological variations of the pastes were examined during soaking in SBF. With the addition of CaF(2), the initial crystalline apatite formation time of the pastes was decreased from three days to one day. After soaking for seven days, the thicknesses of apatite layers depositing on the surface of C(3)S doped with 0, 1, 2 and 3 wt% CaF(2) were about 88, 102, 168 and 136 microm, respectively. C(3)S doped with 2 wt% CaF(2) showed the better ability to induce the formation of apatite. Furthermore, the mechanism of the apatite formation of the CaF(2) doping C(3)S pastes may be attributed to the formation and stability of F-substituted apatite determined by x-ray photoelectron spectroscopy (XPS) at the early age. The results indicated that CaF(2) doping C(3)S has better in vitro bioactivity, and may be used to prepare novel bone cement.This publication has 23 references indexed in Scilit:
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