Epidemiology of Infant Meningococcal Disease in the United States, 2006-2012
Open Access
- 1 February 2015
- journal article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 135 (2), e305-e311
- https://doi.org/10.1542/peds.2014-2035
Abstract
BACKGROUND: The incidence of meningococcal disease is currently at historic lows in the United States; however, incidence remains highest among infants aged Haemophilus influenzae type b and pneumococcal vaccines in infants and children in the United States, Neisseria meningitidis remains an important cause of bacterial meningitis in young children. METHODS: Data were collected from active, population- and laboratory-based surveillance for N meningitidis conducted through Active Bacterial Core surveillance during 2006 through 2012. Expanded data collection forms were completed for infant cases identified in the surveillance area during 2006 through 2010. RESULTS: An estimated 113 cases of culture-confirmed meningococcal disease occurred annually among infants aged CONCLUSIONS: The burden of meningococcal disease remains highest in young infants and serogroup B predominates. Vaccines that provide long-term protection early in life have the potential to reduce the burden of meningococcal disease, especially if they provide protection against serogroup B meningococcal disease.Keywords
This publication has 31 references indexed in Scilit:
- Second hand smoke exposure and the risk of invasive meningococcal disease in children: systematic review and meta-analysisBMC Public Health, 2012
- Bacterial Meningitis in the United States, 1998–2007New England Journal of Medicine, 2011
- Changes inNeisseria meningitidisDisease Epidemiology in the United States, 1998–2007: Implications for Prevention of Meningococcal DiseaseClinical Infectious Diseases, 2010
- Use of Real-Time PCR To Resolve Slide Agglutination Discrepancies in Serogroup Identification of Neisseria meningitidisJournal of Clinical Microbiology, 2004
- Active Bacterial Core Surveillance of the Emerging Infections Program NetworkEmerging Infectious Diseases, 2001
- The Changing Epidemiology of Meningococcal Disease in the United States, 1992–1996The Journal of Infectious Diseases, 1999
- Maternal cigarette smoking and invasive meningococcal disease: a cohort study among young children in metropolitan Atlanta, 1989-1996.American Journal of Public Health, 1999
- Bacterial Meningitis in the United States in 1995New England Journal of Medicine, 1997
- Smoking, the environment and meningococcal disease: a case control studyEpidemiology and Infection, 1994
- Influenza A and meningococcal diseaseThe Lancet, 1991