Preventive or Potential Therapeutic Value of Nutraceuticals against Ionizing Radiation-Induced Oxidative Stress in Exposed Subjects and Frequent Fliers
Open Access
- 20 August 2013
- journal article
- review article
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 14 (8), 17168-17192
- https://doi.org/10.3390/ijms140817168
Abstract
Humans are constantly exposed to ionizing radiation deriving from outer space sources or activities related to medical care. Absorption of ionizing radiation doses over a prolonged period of time can result in oxidative damage and cellular dysfunction inducing several diseases, especially in ageing subjects. In this report, we analyze the effects of ionizing radiation, particularly at low doses, in relation to a variety of human pathologies, including cancer, and cardiovascular and retinal diseases. We discuss scientific data in support of protection strategies by safe antioxidant formulations that can provide preventive or potential therapeutic value in response to long-term diseases that may develop following exposure.This publication has 143 references indexed in Scilit:
- The biological impacts of the Fukushima nuclear accident on the pale grass blue butterflyScientific Reports, 2012
- Radiation as a Risk Factor for Cardiovascular DiseaseAntioxidants and Redox Signaling, 2011
- Signal transduction by reactive oxygen speciesThe Journal of cell biology, 2011
- Cumulative Exposure to Ionizing Radiation From Diagnostic and Therapeutic Cardiac Imaging Procedures: A Population-Based AnalysisJournal of the American College of Cardiology, 2010
- Increased oxidative stress in barn swallows from the Chernobyl regionComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2010
- Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trialThe Lancet, 2008
- Prevention and Treatment of Functional and Structural Radiation Injury in the Rat Heart by Pentoxifylline and Alpha-TocopherolInternational Journal of Radiation Oncology*Biology*Physics, 2008
- Free radicals and antioxidants in normal physiological functions and human diseaseThe International Journal of Biochemistry & Cell Biology, 2007
- Omega-3 fatty acids upregulate adult neurogenesisNeuroscience Letters, 2007
- Inflammation, Atherosclerosis, and Coronary Artery DiseaseThe New England Journal of Medicine, 2005