Analysis of Acidic Drugs in Swiss Wastewaters
- 1 January 2002
- journal article
- research article
- Published by Taylor & Francis Ltd in International Journal of Environmental Analytical Chemistry
- Vol. 82 (10), 659-667
- https://doi.org/10.1080/0306731021000075384
Abstract
Five acidic drugs (clofibric acid, ibuprofen, ketoprofen, mefenamic acid and diclofenac) were chosen in order to determine their behavior in a sewage treatment plant (STP). An analytical method using solid phase extraction (SPE) and a gas chromatograph coupled with a mass spectrometer (GC-MS) was used. The results show that four pharmaceuticals (clofibric acid, ketoprofen, mefenamic acid and diclofenac) are not well removed by treatment in Swiss STPs. Maximum concentration in the effluent was determined for mefenamic acid up to 1.0 µg/L. This component seems to be relevant in Swiss STPs effluents and we can expect its presence in surface waters.Keywords
This publication has 8 references indexed in Scilit:
- Pharmaceuticals and Personal Care Products in the Environment: Agents of Subtle Change?Environmental Health Perspectives, 1999
- Occurrence of antibiotics in the aquatic environmentScience of The Total Environment, 1999
- Occurrence of drugs in German sewage treatment plants and riversWater Research, 1998
- Occurrence and Fate of the Pharmaceutical Drug Diclofenac in Surface Waters: Rapid Photodegradation in a LakeEnvironmental Science & Technology, 1998
- Occurrence, fate and effects of pharmaceutical substances in the environment- A reviewChemosphere, 1998
- Occurrence of the Pharmaceutical Drug Clofibric Acid and the Herbicide Mecoprop in Various Swiss Lakes and in the North SeaEnvironmental Science & Technology, 1998
- Analysis of Phenoxycarboxylic Acids and Other Acidic Compounds in Tap, Ground, Surface and Sewage Water at the Low ng/1 LevelInternational Journal of Environmental Analytical Chemistry, 1995
- Detection of 30 Acidic Herbicides and Related Compounds as Their Pentafluorobenzylic Derivatives Using Gas Chromatography/Mass SpectrometryJournal of AOAC International, 1994