Alterations in the surface properties of cells responsive to nerve growth factor
- 1 June 1978
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 273 (5665), 718-723
- https://doi.org/10.1038/273718a0
Abstract
An initial effect of nerve growth factor on a responsive nerve cell line PC12 cells [rat adrenal pheohromocytoma] is to increase intracellular cyclic AMP, which in turn leads to a mobilization of Ca2+. These events are correlated with structural changes in the plasma membrane, increased cell-substratum adhesion and neurite outgrowth.Keywords
This publication has 24 references indexed in Scilit:
- Biology of Cultured Nerve and MuscleAnnual Review of Neuroscience, 1978
- The maintenance and identification of mouse cerebellar granule cells in monolayer cultureBrain Research, 1977
- Substance P and opiate receptorsNature, 1977
- Induction of differentiation in mouse neuroblastoma cells by hexamethylene bisacetamideBiochemical and Biophysical Research Communications, 1977
- Surface changes in differentiating Friend erythroleukemic cells in cultureCell, 1977
- Insulin Action on Glucose Transport and Calcium Fluxes in Developing Muscle Cells in vitroEuropean Journal of Biochemistry, 1976
- Synaptic vesicle cytochemistry changes when cultured sympathetic neurones develop cholinergic interactionsNature, 1976
- The adhesion of BHK and PyBHK cells to the substratumCell, 1974
- PRIMARY CULTURES OF DISSOCIATED SYMPATHETIC NEURONSThe Journal of cell biology, 1973
- Expression of Differentiated Functions in Mouse Neuroblastoma mediated by Dibutyryl-cyclic Adenosine MonophosphateNature, 1971