Conflict between values and technology: perceptions of preimplantation genetic diagnosis among women at increased risk for hereditary breast and ovarian cancer
- 25 June 2009
- journal article
- Published by Springer Science and Business Media LLC in Familial Cancer
- Vol. 8 (4), 441-449
- https://doi.org/10.1007/s10689-009-9263-7
Abstract
Members of families affected by hereditary cancer are often concerned about passing on risk to offspring. Preimplantation genetic diagnosis is a procedure performed to identify embryos that inherit mutations placing them at risk for hereditary conditions. Little is known about attitudes toward the use of this technology among individuals at risk for hereditary breast and ovarian cancer. We sought to determine high risk women’s attitudes. This study is a qualitative examination of comments from women who participated in an online survey regarding knowledge and attitudes of preimplantation genetic diagnosis among individuals affected by hereditary breast and ovarian cancer. More than half the respondents held less favorable attitudes about the use of preimplantation genetic diagnosis for hereditary breast and ovarian cancer for both themselves and others. However, among the women who felt favorable about its usage, the majority said it became a new option for them to pursue parenthood whereas previously they had opted to not have a biological child. The high percentage of respondents who have never heard of preimplantation genetic diagnosis and who were in favor of this technology for hereditary breast and ovarian cancer indicates the need for educational campaigns to increase awareness and provide information about the procedure, access and affordability. Further research is needed to determine how this population would like this information presented to them and how best to instruct health care professionals to present this topic to women who do not know to ask about it.Keywords
This publication has 31 references indexed in Scilit:
- Patient willingness to participate in a clinical trial with preimplantation genetic diagnosisFertility and Sterility, 2008
- Cancer risk reduction and reproductive concerns in female BRCA1/2 mutation carriersFamilial Cancer, 2007
- Preimplantation genetic diagnosis: public policy and public attitudesFertility and Sterility, 2006
- Opinions about new reproductive genetic technologies: Hopes and fears for our genetic futureFertility and Sterility, 2005
- Preimplantation Genetic Diagnosis—An OverviewJournal of Histochemistry & Cytochemistry, 2005
- Generation of Knowledge for Reproductive Health Technologies: Constraints on Social and Behavioral ResearchJournal of Social Issues, 2005
- Empowering primary care health professionals in medical genetics: How soon? How fast? How far?American Journal of Medical Genetics, 2001
- An inevitable dilemma: Prenatal testing for mutations in the brca1 breast-ovarian cancer susceptibility geneObstetrics & Gynecology, 1996
- Identification of the breast cancer susceptibility gene BRCA2Nature, 1995
- Toward a Methodology of Naturalistic Inquiry in Educational EvaluationEducational Evaluation and Policy Analysis, 1979