Human Plasmodium knowlesi infections in young children in central Vietnam
Open Access
- 30 October 2009
- journal article
- case report
- Published by Springer Science and Business Media LLC in Malaria Journal
- Vol. 8 (1), 1-5
- https://doi.org/10.1186/1475-2875-8-249
Abstract
Considering increasing reports on human infections by Plasmodium knowlesi in Southeast Asian countries, blood samples collected during two large cross-sectional malariometric surveys carried out in a forested area of central Vietnam in 2004 and 2005 were screened for this parasite. Blood samples collected at the 2004 survey and positive for Plasmodium malariae were randomly selected for PCR analysis detecting P. knowlesi. Blood samples collected in 2005 from the same individuals were screened again for P. knowlesi. Positive samples were confirmed by sequencing. Family members of positive cases who participated in both surveys were also screened. Ninety-five samples with P. malariae mono- or mixed infections identified by species-specific PCR were screened for P. knowlesi. Among the five (5.2%) positive samples by PCR, three were confirmed to be P. knowlesi infections by sequencing, two young children (Plasmodium knowlesi infections in humans can be found in central Vietnam. A small child was positive for P. knowlesi in both surveys at one year interval, though it is unclear whether it was the same or a new infection.Keywords
This publication has 23 references indexed in Scilit:
- Long-Lasting Insecticidal Hammocks for Controlling Forest Malaria: A Community-Based Trial in a Rural Area of Central VietnamPLOS ONE, 2009
- Swedish traveller with Plasmodium knowlesi malaria after visiting Malaysian BorneoMalaria Journal, 2009
- Rapid decrease of malaria morbidity following the introduction of community-based monitoring in a rural area of central VietnamMalaria Journal, 2009
- Comparative genomics of the neglected human malaria parasite Plasmodium vivaxNature, 2008
- Knowlesi malaria: newly emergent and of public health importance?Trends in Parasitology, 2008
- Naturally Acquired HumanPlasmodium knowlesiInfection, SingaporeEmerging Infectious Diseases, 2008
- Bionomics of Anopheles latens in Kapit, Sarawak, Malaysian Borneo in relation to the transmission of zoonotic simian malaria parasite Plasmodium knowlesiMalaria Journal, 2008
- Plasmodium knowlesi Malaria in Humans Is Widely Distributed and Potentially Life ThreateningClinical Infectious Diseases, 2008
- Plasmodium knowlesi in humans, macaques and mosquitoes in peninsular MalaysiaParasites & Vectors, 2008
- The Anopheles dirus complex: spatial distribution and environmental driversMalaria Journal, 2007