The SMC family: from chromosome condensation to dosage compensation
- 31 December 1995
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Cell Biology
- Vol. 7 (3), 329-336
- https://doi.org/10.1016/0955-0674(95)80087-5
Abstract
Recent genetic analyses in yeasts and biochemical studies in vertebrate cells have led to the discovery of a family of putative ATPases that play a fundamental role in chromosome condensation and segregation in mitosis. One of the members was also found to be involved in dosage compensation in Caenorhabditis elegans, providing a new link between global regulation of gene expression and chromosome structure. This unique family of proteins may control higher-order chromosome dynamics by regulated self-assembly or mechanochemical activity.Keywords
This publication has 42 references indexed in Scilit:
- A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitroCell, 1994
- Role of nonhistone proteins in the chromosomal events of mitosisThe FASEB Journal, 1994
- Chromosome Condensation in Xenopus Mitotic Extracts Without Histone H1Science, 1993
- SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family.The Journal of cell biology, 1993
- Chromosome structure inside the nucleusCurrent Opinion in Cell Biology, 1993
- Chromatin condensation: does histone H1 dephosphorylation play a role?Trends in Biochemical Sciences, 1992
- Reversible histone modification and the chromosome cell cycleBioEssays, 1992
- Large scale chromosome structure and organization: Current opinion in structural biology 1991, 1: 237–244Current Opinion in Structural Biology, 1991
- A glimpse at chromosomal orderTrends in Genetics, 1987
- Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.The Journal of cell biology, 1979