Gamma Knife thalamotomy for treatment of essential tremor: long-term results
- 1 June 2010
- journal article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 112 (6), 1311-1317
- https://doi.org/10.3171/2009.10.jns09332
Abstract
Object The goal of this report was to describe the safety and effectiveness of nucleus ventralis intermedius (VIM) thalamotomy performed with the Leksell Gamma Knife (GK) for the treatment of essential tremor (ET). Methods One hundred seventy-two patients underwent a total of 214 VIM thalamotomy procedures with the Leksell GK between February 1994 and March 2007 for treatment of disabling ET. Eleven patients were lost to follow-up less than 1 year after the procedures, so that in this report the authors describe the results in 161 patients who underwent a total of 203 thalamotomies (119 unilateral and 42 bilateral). Results There were statistically significant decreases (p < 0.0001) in tremor scores for both writing and drawing. The mean postoperative follow-up duration for all patients was 44 ± 33 months. Fifty-four patients have been followed for more than 60 months posttreatment. There were 14 patients who suffered neurological side effects that were temporary (6) or permanent (8), which accounted for ...Keywords
This publication has 44 references indexed in Scilit:
- REOPERATION FOR SUBOPTIMAL OUTCOMES AFTER DEEP BRAIN STIMULATION SURGERYNeurosurgery, 2008
- Clinical Cases where Lesion Therapy Was Chosen over Deep Brain StimulationStereotactic and Functional Neurosurgery, 2008
- Rating Scales for Clinical Studies in Neurology—Challenges and OpportunitiestouchREVIEWS in Neurology, 2008
- Psychiatric and neuropsychiatric adverse events associated with deep brain stimulation: A meta‐analysis of ten years' experienceMovement Disorders, 2007
- Deep brain stimulation in the subthalamic area is more effective than nucleus ventralis intermedius stimulation for bilateral intention tremorActa Neurochirurgica, 2007
- Thalamic deep brain stimulation in the treatment of essential tremor: a long-term follow-upBritish Journal Of Neurosurgery, 2007
- Hardware-Related Complications of Deep Brain Stimulation: A Review of the Published LiteratureStereotactic and Functional Neurosurgery, 2006
- Safety considerations for deep brain stimulation: review and analysisExpert Review of Medical Devices, 2005
- Central Mechanisms of TremorJournal Of Clinical Neurophysiology, 1996
- A study of hereditary essential tremorBrain, 1994