Myeloid-Antigen Expression in Adult Acute Lymphoblastic Leukemia
- 29 October 1987
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 317 (18), 1156-1157
- https://doi.org/10.1056/nejm198710293171814
Abstract
To the Editor: Recently, Sobol et al. (April 30 issue)1 studied the expression of myeloid antigen in adult acute lymphoblastic leukemia (ALL). Surprisingly, patients who were positive for the antigen (My+) accounted for 33 percent of the series, being positive for MCS-2 (CD13), MY9 (CD33), or both. I would like to comment on some points.To include My+ cases that are negative for B-cell and T-cell markers and showed germ-line configurations of immunoglobulin and T-cell receptor genes as "pure myeloid-antigen phenotypes" in a group with ALL is a rather uncommon practice. Not surprisingly, none of these patients had a . . .Keywords
This publication has 5 references indexed in Scilit:
- Clinical Importance of Myeloid Antigen Expression in Adult Acute Lymphoblastic LeukemiaNew England Journal of Medicine, 1987
- 11 Lineage Heterogeneity in Acute Leukaemia: Acute Mixed-lineage Leukaemia and Lineage SwitchClinics in Haematology, 1986
- Adult acute lymphoblastic leukemia phenotypes defined by monoclonal antibodiesBlood, 1985
- Reproducibility of the French-American-British classification of acute Leukemia: The southwest oncology group experienceAmerican Journal of Hematology, 1985
- Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative GroupBritish Journal of Haematology, 1976