Vinylcyclopropane Derivatives in Transition-Metal-Catalyzed Cycloadditions for the Synthesis of Carbocyclic Compounds
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- 25 June 2013
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 78 (14), 6842-6848
- https://doi.org/10.1021/jo400609w
Abstract
Vinylcyclopropane (VCP) derivatives participate in a variety of transition-metal-catalyzed multicomponent cycloadditions to produce five- to eight-membered carbocycles. Various cycloaddition modes provide novel approaches to mono-, bi-, and polycyclic molecules. In this Synopsis, recent advances in transition-metal-catalyzed VCP cycloadditions are discussed, with a particular emphasis on the influence of VCP substitution pattern on cycloaddition modes. A tabular summary of applications of the VCP cycloadditions in natural product synthesis is also presented.Keywords
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