Sonographic prediction of chronic lung disease in the premature undergoing mechanical ventilation
- 1 July 1996
- journal article
- Published by Springer Science and Business Media LLC in Pediatric Radiology
- Vol. 26 (7), 463-469
- https://doi.org/10.1007/bf01377203
Abstract
The aims of the study are to investigate the possible role of ultrasound (US) of the chest in predicting the development of chronic lung disease (CLD) in patients with hyaline membrane disease (HMD) and to determine the optimal age for the sonographic examination. One hundred and five consecutive prematures undergoing mechanical ventilation were prospectively studied by US of the chest. The US examinations were performed at birth and at least once a week until discharge from the neonatal unit. The sonographic patterns observed behind the diaphragm and their evolutions were recorded and correlated with the clinical and radiological data at day 28, which corresponds to the currently accepted limit for determining the presence of CLD. CLD is currently defined as oxygen dependency on day 28 with radiographic abnormalities. A diffuse retrodiaphragmatic hyperechogenicity was observed in all the patients with HMD. The hyperechogenicity resolved completely in patients with an uncomplicated clinical evolution. In contrast, in patients with CLD the hyperechogenicity resolved only partially, resulting in less diffuse and less extensive hyperechogenicity. Day 18 was the earliest day where the persistence of the abnormal retrodiaphragmatic hyperechogenicity was observed in 100 % of the patients presenting CLD at day 28. At that time, 95.2 % of the patients without abnormal hyperechogenicity showed uncomplicated evolution and no CLD. US can be a useful diagnostic tool to determine the occurrence of CLD and to predict as early as day 18 the prematures at risk for the disease.Keywords
This publication has 19 references indexed in Scilit:
- The relationship of pulmonary interstitial emphysema to subsequent type of chronic lung diseaseThe British Journal of Radiology, 1994
- Prediction of chronic lung disease from the chest radiograph appearance at seven days of ageActa Paediatrica, 1993
- Correlations between radiological and cytological findings in early development of bronchopulmonary dysplasiaEuropean Journal of Pediatrics, 1993
- Microscopic observations on tracheal aspirates from ventilated neonatesEuropean Journal of Pediatrics, 1992
- Bronchopulmonary dysplasia: early diagnosis, prophylaxis, and treatment.Archives of Disease in Childhood, 1990
- Hyaline membrane disease in the newborn: Diagnosis by ultrasoundPediatric Radiology, 1990
- The changing pattern of chronic lung disease of prematurity.Archives of Disease in Childhood, 1989
- The air bronchogram: sonographic demonstrationAmerican Journal of Roentgenology, 1986
- Early prediction of chronic lung disease by pulmonary function testingThe Journal of Pediatrics, 1983
- A TECHNIQUE FOR CORRELATING THE ROENTGENOLOGIC APPEARANCE OF INFANT LUNG TO ITS ANATOMYAmerican Journal of Roentgenology, 1973