Experimental Infection of Cattle with SARS-CoV-2

Abstract
We inoculated 6 cattle with severe acute respiratory syndrome coronavirus 2 and kept them together with 3 in-contact, virus-naive cattle. We observed viral replication and specific seroreactivity in 2 inoculated animals, despite high levels of preexisting antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected.